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rfdiffusion
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# RFdiffusion Backbone Generation
Diffusion-based de novo protein backbone generation. Use for: binder scaffolds targeting specific hotspot residues, novel fold generation, motif scaffolding, and symmetric oligomer design.
## Requirements
- Python 3.9+
- 16–24 GB GPU VRAM (A100 recommended for large designs)
- ~2 GB disk for model weights
## Installation
```bash
# Via SE3-Diffusion environment (recommended)
conda create -n rfdiffusion python=3.9