Individual skill
waypoint-bio
Use when working with Outpost Bio's open microbiome foundation models - the Waypoint checkpoints (Waypoint-6m, Waypoint-45m, Waypoint-170m), the Atlas pretraining corpus, the Compass eight-task benchmark, or the `waypoint` CLI from the `waypoint-bio` package. Covers embedding microbiome samples, fine-tuning on taxonomic abundance data, benchmarking a checkpoint on Compass, pretraining a GPT-2 model on taxonomic abundance profiles, and converting MetaPhlAn, Kraken2, QIIME 2, or MGnify abundance tables into waypoint format.
plugins/KalarisLabs/research-agent-skills/skills/waypoint-bio/SKILL.md
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- Nov 6, 2026
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- Apache-2.0
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# Waypoint: Outpost Bio's Open Microbiome Foundation Models
## Overview
Outpost Bio open-sourced three artefacts under Apache 2.0, described in
[Treloar et al., bioRxiv 2026.05.02.722381](https://www.biorxiv.org/content/10.64898/2026.05.02.722381v2):
| Artefact | What it is | Hugging Face |
| --- | --- | --- |
| **Waypoint** | GPT-2-style causal LMs over taxonomic tokens, 6M–170M params | `outpost-bio/Waypoint-6m`, `-45m`, `-170m` |
| **Atlas** | 539,308 microbiome samples scraped from MGnify (485,377 pretrain / 53,931 benchmark) | `outpost-bio/Atlas` |
| **Compass** | Eight downstream tasks over four studies | `outpost-bio/Compass` |
The unifying idea: a microbiome sample is a *sentence*. Each taxon is one token, tokens are ordered