Individual skill
onekgpd
Query the 1000 Genomes Project dataset (3,202 whole-genome-sequenced individuals, GRCh38) at the level of individual participants. Use when a question is about individuals or variants in the 1000 Genomes Project cohort: which individuals carry variants matching specific criteria in a gene or region, which individuals are homozygous-reference at a position, which variants exist in the dataset or carried by specified individuals in a gene or region, the relatedness between two specified individuals. Variants are returned with 1000 Genomes allele frequencies (AF), gnomAD v4.1 exome and genome AF, AlphaMissense score, and HGVSp annotations.
plugins/KalarisLabs/research-agent-skills/skills/onekgpd/SKILL.md
Source commit d780783eba4ecc7c8b9429f95c9362df95f07c61
What was checked
- Matches the observed repository HEAD
- Yes
- Scanner rules are current
- Yes
- Repository scan complete
- No
- Skill scan complete
- No
- Observed behavior
- Network or broad shell
- Last checked
- Nov 4, 2026
These are observations at the recorded commit, not a guarantee of safety. Review the source before running it.
Install this skill
Choose an agent in your Stack or copy a command below. Commands fetch the pinned commit and copy only this skill directory. Existing destinations are refused. Copying a command does not install anything.
An install command is unavailable: current rules, complete repository and skill scans, an eligible behavior level and a permitted license are required.
Repository context
- Repository stars (not skill ratings)
- 1,531
- Repository last updated
- Nov 6, 2026
- License
- Apache-2.0
Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.
- ai-coding Repository topic
- awesome Repository topic
- awesome-list Repository topic
- codex Repository topic
- codex-plugins Repository topic
- openai Repository topic
- codex-skill Repository topic
- codex-skills Repository topic
- marketplace Repository topic
- codex-marketplace Repository topic
- engineering Derived category
Declared tags are partial or unavailable.
Files and excerpt
File metadata and permitted, redacted excerpts come from the recorded scan. Source links are pinned to that commit.
Browse files
SKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesSKILL.mdcore · 20,754 bytesassets/kgpe.jsonasset · 1,037,258 bytesreferences/annotation_vocabularies.mddoc · 4,457 bytesreferences/onekgpd_commands.mddoc · 13,851 bytesscripts/onekgpd_api.pyruns · 30,639 bytesscripts/onekgpd_meta.pyruns · 19,625 bytes
Read excerpt
# OneKGPd: Individual-Level Queries over the 1000 Genomes Project
## Scope
This skill queries the 1000 Genomes Project dataset — the extended high-coverage cohort
of 3,202 whole-genome-sequenced individuals, on the GRCh38 assembly. All results
are drawn from this cohort, and sample names returned by the skill (for example
`HG00096` or `NA21130`) identify its participants.
Queries resolve against the cohort's per-individual genotype data. This supports
two complementary classes of question: selecting **variants** carried within a
region (across the whole cohort or within a specified set of individuals), and
selecting the **individuals** who carry variants matching given criteria.
Variant selection can be filtered by allele frequency, predicted consequence,