Individual skill
statistical-power
Sample-size and statistical power calculations for planning studies. Use whenever someone asks "how many subjects/samples/replicates do I need", wants an a priori power analysis, a minimum detectable effect (MDE), a power curve, or needs to justify a sample size for a grant, IRB protocol, or pre-registration. Covers closed-form power for t-tests, ANOVA, proportions, correlations, chi-square, and regression, plus simulation-based (Monte Carlo) power for designs with no formula — logistic/Poisson regression, mixed models, cluster-randomized trials, survival, and interactions. Use this skill even when the request only mentions an effect size, alpha, or "80% power" without saying "power analysis" explicitly. For laying out the study (randomization, blocking, factorial/DOE, crossover, sequential designs) use experimental-design; for analyzing data already collected and reporting it use statistical-analysis.
plugins/KalarisLabs/research-agent-skills/skills/statistical-power/SKILL.md
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- Last checked
- Nov 4, 2026
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- Repository last updated
- Nov 6, 2026
- License
- Apache-2.0
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- power-analysis,-sample-size,-study-design,-statistics Declared skill tag
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SKILL.mdcore · 16,305 bytesSKILL.mdcore · 16,305 bytesSKILL.mdcore · 16,305 bytesSKILL.mdcore · 16,305 bytesSKILL.mdcore · 16,305 bytesreferences/closed_form_recipes.mddoc · 6,809 bytesreferences/effect_sizes.mddoc · 4,919 bytesreferences/simulation_based_power.mddoc · 5,684 bytesscripts/power.pyruns · 12,726 bytesscripts/simulate_power.pyruns · 8,009 bytes
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# Statistical Power & Sample Size
## Overview
Power analysis answers one of the most consequential questions in study planning: **how large a sample do you need to reliably detect an effect of a given size, and what could you detect with the sample you can afford?** An underpowered study wastes resources and produces inconclusive or irreproducible results; an overpowered one wastes participants, money, and (in clinical work) exposes more people to risk than necessary. Getting this right *before* data collection is the single highest-leverage statistical decision in a project.
Four quantities are locked together for any given test: **sample size (n)**, **effect size**, **significance level (α)**, and **power (1 − β)**. Fix any three and the fourth is determined. Every calculation in this skill is some rearrangement of that relationship.
This skill covers the two ways to do power analysis:
- **Closed-form** formulas (fast, exact for standard tests) — see `references/closed_form_recipes.md`.
- **Simulation / Monte Carlo** (works for *any* design or model you can simulate and analyze) — see `references/simulation_based_power.md`.
For choosing and converting effect sizes — usually the hardest part — see `references/effect_sizes.md`.