Individual skill
fine-mapping
Statistical fine-mapping of GWAS loci using SuSiE, SuSiE-inf, and Approximate Bayes Factors to identify credible sets and posterior inclusion probabilities (PIPs) for causal variant discovery. SuSiE-inf adds an infinitesimal polygenic component for improved calibration at well-powered loci.
skills/fine-mapping/SKILL.md
Source commit df61706c3e32fea21ad88f5b8a5189c895f9524d
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- Last checked
- Nov 8, 2026
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Repository context
- Repository stars (not skill ratings)
- 1,175
- Repository last updated
- Nov 7, 2026
- License
- NOASSERTION
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- ai-agents Repository topic
- bioinformatics Repository topic
- equity Repository topic
- genomics Repository topic
- local-first Repository topic
- openclaw Repository topic
- population-genetics Repository topic
- reproducibility Repository topic
- gwas Declared skill tag
- fine-mapping Declared skill tag
- susie Declared skill tag
- credible-sets Declared skill tag
- pip Declared skill tag
- causal-variants Declared skill tag
- statistics Declared skill tag
- data Derived category
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SKILL.mdcore · 14,730 bytesSKILL.mdcore · 14,730 bytesSKILL.mdcore · 14,730 bytesSKILL.mdcore · 14,730 bytesSKILL.mdcore · 14,730 bytesSKILL.mdcore · 14,730 bytescore/__init__.pyruns · 0 bytescore/abf.pyruns · 2,344 bytescore/credible_sets.pyruns · 5,499 bytescore/io.pyruns · 6,016 bytescore/report.pyruns · 22,125 bytescore/susie.pyruns · 8,861 bytescore/susie_inf.pyruns · 13,456 bytesfine_mapping.pyruns · 15,461 bytesfine_mapping_core/__init__.pyruns · 0 bytesfine_mapping_core/abf.pyruns · 2,344 bytesfine_mapping_core/credible_sets.pyruns · 5,499 bytesfine_mapping_core/io.pyruns · 6,016 bytesfine_mapping_core/report.pyruns · 22,125 bytesfine_mapping_core/susie.pyruns · 8,861 bytesfine_mapping_core/susie_inf.pyruns · 13,456 bytestests/fixtures/demo_susie_known_answer.jsonasset · 1,567 bytestests/test_fine_mapping.pyruns · 54,454 bytes
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