Individual skill
gwas-sumstats-harmonize
Harmonize GWAS summary statistics from any common format (GWAS-Catalog SSF, PLINK 1.9/2, REGENIE, METAL, BOLT, SAIGE) to one canonical table (SNP CHR BP EA NEA EAF BETA SE P N): column detection, BETA/SE/P derivation, QC with drop reasons, and allele alignment to a reference panel, run as a Snakemake workflow.
skills/gwas-sumstats-harmonize/SKILL.md
Source commit df61706c3e32fea21ad88f5b8a5189c895f9524d
What was checked
- Matches the observed repository HEAD
- Yes
- Scanner rules are current
- Yes
- Repository scan complete
- No
- Skill scan complete
- No
- Observed behavior
- Network or broad shell
- Last checked
- Nov 8, 2026
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Repository context
- Repository stars (not skill ratings)
- 1,176
- Repository last updated
- Nov 7, 2026
- License
- NOASSERTION
Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.
- ai-agents Repository topic
- bioinformatics Repository topic
- equity Repository topic
- genomics Repository topic
- local-first Repository topic
- openclaw Repository topic
- population-genetics Repository topic
- reproducibility Repository topic
- gwas Declared skill tag
- summary-statistics Declared skill tag
- harmonization Declared skill tag
- allele-alignment Declared skill tag
- meta-analysis Declared skill tag
- snakemake Declared skill tag
- operations Derived category
- data Derived category
Files and excerpt
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Browse files
SKILL.mdcore · 16,935 bytesSKILL.mdcore · 16,935 bytesSKILL.mdcore · 16,935 bytesSKILL.mdcore · 16,935 bytesSKILL.mdcore · 16,935 bytesexamples/cohort_metal.tblasset · 9,416 bytesexamples/cohort_plink2.glm.logisticasset · 12,296 bytesexamples/cohort_regenie.regenieasset · 12,084 bytesexamples/cohort_saige.txtdoc · 16,345 bytesexamples/cohort_ssf.tsvasset · 12,162 bytesexamples/demo_manifest.yamlasset · 669 bytesexamples/make_demo_data.pyruns · 6,352 bytesexamples/reference.tsvasset · 4,306 bytesgwas_sumstats_harmonize.pyruns · 22,021 bytestests/test_gwas_sumstats_harmonize.pyruns · 41,728 bytesworkflow/Snakefileasset · 2,188 bytesworkflow/config/config_loader.pyruns · 4,616 bytesworkflow/envs/python.yamlasset · 194 bytesworkflow/rules/align_reference.smkasset · 1,275 bytesworkflow/rules/common.smkasset · 292 bytesworkflow/rules/derive_effects.smkasset · 875 bytesworkflow/rules/map_columns.smkasset · 907 bytesworkflow/rules/qc_filter.smkasset · 1,155 bytesworkflow/scripts/align_reference.pyruns · 6,411 bytesworkflow/scripts/derive_effects.pyruns · 5,026 bytesworkflow/scripts/lib/harmonize_lib.pyruns · 13,838 bytesworkflow/scripts/map_columns.pyruns · 5,244 bytesworkflow/scripts/qc_filter.pyruns · 5,333 bytes
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