Individual skill

histone-aggregation

Build comprehensive histone mark maps by aggregating narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is this histone mark present in my tissue?" by combining peak calls from multiple studies into a union peak set with confidence annotations. Handles cross-lab batch effects, broad vs narrow marks, and ENCODE blocklist filtering.

plugin/skills/histone-aggregation/SKILL.md

Source commit 36836c8725fd4d20d9c851ce314f5151aea5f57c

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Yes

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No

Observed behavior

Network or broad shell

Last checked

Nov 6, 2026

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