Individual skill
spike-sorting
Spike sorting for extracellular electrophysiology — detection, clustering, and quality metrics for single units.
skills/spike-sorting/SKILL.md
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- License
- MIT
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## Overview
spike-sorting is the process of detecting action potentials in extracellular recordings and assigning
each spike to the neuron that produced it. It is the gateway to single-unit neuroscience: every
tuning curve, place field, and decoding result downstream depends on sorting done honestly.
Modern high-density probes (Neuropixels) record hundreds of neurons simultaneously, and the field has
moved from manual cluster-cutting to automated sorters (Kilosort, MountainSort, SpyKING Circus) plus
manual curation. The skill covers choosing a sorter, validating its output, and the quality metrics
that separate real single units from multi-unit hash.
## When to use
- Planning a recording: probe choice, sampling rate (≥20-30 kHz), reference strategy.